How to Pronounce Karst Hoogsteen
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Oct 01, 1923 Groningen, Netherlands Died on 10 Aug 2015 (aged 91)
biochemist
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About Karst Hoogsteen
- Karst Hoogsteen (October 1, 1923 – August 10, 2015) was a Dutch-born American biochemist famous for noting a new base pairing form in DNA, now called Hoogsteen base pairs.
- These base pairing intercede in the Watson-Crick base pairing, forging a base pair 'triplex'.
- The Base Pairs use the N7 nitrogen atom as the accepter rather than the N1 as observed in Watson-Crick base pairing.
- This leads to a twisted, non-linear arrangement.
