How to Pronounce Bartolomeo Gosio
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Mar 17, 1863 Magliano Alfieri, Piedmont, Italy Died on 13 Apr 1944 (aged 81)
Italian physician, microbiologist and biochemist
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About Bartolomeo Gosio
- Bartolomeo Gosio (17 March 1863 – 13 April 1944) was an Italian medical scientist.
- He discovered a toxic fume, eponymously named "Gosio gas", which is produced by microorganisms, that killed many people.
- He identified the chemical nature of the gas as an arsenic compound (arsine), but incorrectly named it as diethylarsine.
- He also discovered an antibacterial compound called mycophenolic acid from the mould Penicillium brevicompactum.
- He demonstrated that the novel compound was effective against the deadly anthrax bacterium, Bacillus anthracis.
- This was the first antibiotic compound isolated in pure and crystallised form.
- Though the original compound was abandoned in clinical practice due to its adverse effects, its chemical derivative mycophenolate mofetil became the drug of choice as an immunosuppressant in kidney, heart, and liver transplantations.
